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KMID : 0358119910170020111
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Journal of the Korean Public Health Association
1991 Volume.17 No. 2 p.111 ~ p.129
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EFFECTS OF KRILL POWDER ON LIPID COMPONENTS OF PLASMA, LIVER AND HEART IN CHOLESTEROL AND CADMIUMFED RATS
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Abstract
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In order to investigate effects of krill, which have high quality protein and polyunsaturated fatty acid(PUFA) content, on lipid components of plasma, liver and heart in cholesterol and cadmium-fed rats, forty-eight male rats Sprague-Dawley strain weighed 200+19g were divided into 8 diet groups of 4 parts (standard diet, control diet, krill diet and krill plus cadmium diet) and fed for 4 weeks.
The results obtained were summarized as follows
1. Krill used in this experiment-contained protein 65.4% (w/w) and lipid 16.7% unsaturated fatty acid was 2 times higher than saturated fatty acid and PUFA content was 35.2 % from among fatty acids. Amino acid content was high in order of Glu, Asp, Tyr and Lys. Essential amino acid was about 40 % and its composition was even approximately. 2. Krill diets were significantly greater than the control diet in body weight gain (P<0. 05). Liver weight and RLS ratio was not significantly difference but approximately high. Heart was not significantly difference. In cadmium diet, change of weight was showed to be in order of body, liver and heart. Body and liver weight were significantly difference (p <0.05).
3. Krill diets were significantly greater than the control diet in food intake.´ Food of f iency ratio (FER) was slightly higher but not significantly. In cadmium diets, FER was very significantly low in comparison with food intake and water consumption was: 10w. 4. The total cholesterol concentration of plasma in krill diets were lower than that in control diet, but HDL-cholesterol concentration and ratio of HDL-cholesterol to total cholesterol concentration were high. In cadmium diets, their values were contrary. 5. The free cholesterol and cholesterol ester concentration of plasma in krill diets were lower than that in control diet, but ratio of cholesterol ester to total ´, cholesterol concentration were high. In cadmium diets, their values were contrary.
6.8-Lipoprotein and LDL-cholesterol concentration of plasma in krill diets were lower than those in control diet but very significantly high in cadmium diets (P<0.05). 7. Phospholipid and triglyceride concentration of plasma in krill diets were lower than those in the control diet. In cadmium diet, triglyceride was significantly high but phospholipid was not difference.
8. The contents of total cholesterol and free cholesterol of liver and heart in krill diets were similar or slightly great. In cadmium diets, their values were similar or low.
9. The contents of phospholipid and triglyceride of liver in krill diets were higher than those in cotrol diet. In heart, phospholipid was high and triglyceride was low. In cadmium diets, phospholipid and triglyceride were similar or low.
10. The concentration of cadmium of plasma in krill diets was significantly increased by adding krill powder in comparison {with control diet group. In liver, it was low and in´´ heart, high.
11. Lipid accumulation of liver tissue by Hematoxylin-Eosin method was observed in all
diets groups but no differences were found among their groups. Necrosis and hemolysis of liver in all diets groups were not shown.
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